Comparative in vitro activities of N-formimidoyl thienamycin and moxalactam against nonfermentative aerobic gram-negative rods.
نویسندگان
چکیده
N-Formimidoyl thienamycin was the most active drug against strains of Pseudomonas aeruginosa with a 90% minimum inhibitory concentration of 1.25 mug/ml. With the exception of P. maltophilia, thienamycin was as active or more active than moxalactam against other species of pseudomonads and against other genera of nonfermenters.
منابع مشابه
Comparative in vitro susceptibilities of anaerobic bacteria to cefmenoxime, cefotetan, and N-formimidoyl thienamycin.
The in vitro activities of cefmenoxime, cefotetan, and N-formimidoyl thienamycin were compared with those of other antimicrobial agents (metronidazole, clindamycin, cefoxitin, and moxalactam) against anaerobic bacteria. The data obtained indicate that N-formimidoyl thienamycin exhibits excellent activity against anaerobic bacteria; cefotetan and cefmenoxime, though less active, should be of val...
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The in vitro activity of N-formimidoyl thienamycin (MK0787), a stable congener of thienamycin, was determined against 200 species of aerobic and 84 species of anaerobic bacteria. The compound was highly active against resistant gram-negative bacilli, penicillin-resistant Staphylococcus aureus, enterococci, and anaerobic bacteria. The new derivative of thienamycin was more active than the parent...
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عنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 21 4 شماره
صفحات -
تاریخ انتشار 1982